Ossifying Collagen Sponge
Powered by GLYMATRIX® Technology
for Guided Bone (GBR) and Tissue (GTR) Regeneration
Why OSSIX™ Bone Stands Out
In dental bone regeneration, long term success is closely linked to the quality and vitality of the bone involved in the process. Vital bone, unlike non-vital or necrotic bone, offers high blood supply and enhanced cellular activity.
OSSIX™ Bone is a collagen sponge for Guided Bone Regeneration (GBR) and Guided Tissue Regeneration (GTR).3 This innovative ossifying collagen sponge1-2, powered by GLYMATRIX® technology2, is specifically designed to maximize vital bone formation1—offering significant higher percentage over competing products at 4-months healing time point.1
Key Advantages of OSSIX™ Bone:
- Higher Vital Bone Percentage: OSSIX™ Bone yields a significantly higher percentage of vital bone compared to other xenograft materials. 1,3-5 This means better integration with surrounding tissues, leading to more predictable and successful outcomes.
- No Residual Graft Particles: OSSIX™ Bone undergoes complete ossification, leaving behind no residual graft particles. 1 The result is true bone formation, free from foreign material, ensuring the long-term health and stability of the regenerated area.
- Excellent Vascularization and Cellular Proliferation: The composition of sugar cross-linked collagen and hydroxyapatite microparticles creates an environment that promotes the formation of new blood vessels and supports the cellular activities necessary for robust bone maturation. 3,6
- User-Friendly: Easy to handle and apply, product structure is preventing unwanted movement of particles.1,3,4,7
- Cost-Effective: Reduces the need for additional materials like membranes in certain procedures,1,4 making it a more economical choice for both practitioners and patients.
- Proven Efficacy: Powered by GLYMATRIX® Technology,2 backed by clinical studies and real-world applications, OSSIX™ Bone delivers consistent and predictable outcomes.1-7
Applications of OSSIX™ Bone*
OSSIX™ Bone is versatile and effective for a wide range of dental and periodontal procedures:
- Alveolar Ridge Augmentation: Ideal for reconstructive treatment of the alveolar ridge, supporting implant placement and overall oral structure.
- Periodontal and Peri-Implant Defects: Fills periodontal and peri-implant defects, effectively supporting Guided Tissue Regeneration (GTR) and Guided Bone Regeneration (GBR) procedures.
- Socket Preservation Post-Extraction: Enhances alveolar ridge preservation following tooth extractions, preparing the site for future implants.
- Sinus Floor Elevation: Provides reliable support in maxillary sinus floor elevation, promoting successful bone regeneration.
- Root Resection, Apicoectomy, and Cystectomy: Fills defects post-procedures like root resection, apicoectomy, and cystectomy, aiding in the regeneration and healing process.
*For detailed guidance on indications and contraindications, refer to the Instructions for Use (IFU) available in our IFU Library.
Sizing Options:
OSSIX™ Bone is available in three convenient sizes to fit your clinical needs:
| 5x5x5 mm (0.125 cc) |
5x5x10 mm (0.25 cc) |
5x10x10 mm (0.50 cc) |
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*Images shown are not to scale.
ReferencesReferences1. Lorenc ZP, Nir E, Azachi M, Characterization of Physical Properties and Histologic Evaluation of Injectable Dermicol-P35 Porcine-Collagen Dermal Filler. 2010, Plast. Reconstr. Surg. 125: 1805.
2. Eliezer, M. and A. Friedmann, Bone regeneration around immediate implant placement using only GLYMATRIX technology P429. 2019. Abstract at Osteology,.
3. Zubery, Y., et al., Ossification of a novel cross-linked porcine collagen barrier in guided bone regeneration in dogs. J Periodontol, 2007. 78(1): p. 112-21.
4. Chackartchi, T., et al., A novel surgical approach to modify the periodontal phenotype for the prevention of mucogingival complications related to orthodontic treatment. Int J Periodontics Restorative Dent, 2021. 41(6): p. 811-817.
5. Neiva R. Evolution of biomaterials in implant dentistry leads toenhanced tissue quality. Compend Contin Educ Dent. 2022;43(7): 454-455.
6. Data on file.
7. Volumetric Outcomes of Peri-implant Soft Tissue Augmentation with a Xenogeneic Cross-Linked Collagen Scaffold: A Comparative Clinical Study. Int J Periodontics Restorative Dent. 2023 Jul-Aug;43(4):415-422.
8. Marina Brant-Roznavi, Dror Aizenbud. OSSIX Volumax Collagen Scaffold Characterization by Cell Proliferation, Differentiation and Vascularization, Rambam Health Care Campus, Faculty of Medicine –Technion, Israel, 2017
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