Ossifying Collagen Barrier Membrane
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for Guided Bone (GBR) and Tissue (GTR) Regeneration
Why OSSIX® Plus?
Different membranes exhibit varying resorption patterns after implantation, significantly influencing clinical outcomes. Studies have shown that the amount of residual membrane material can vary considerably between different membranes, affecting the healing process and overall success of the procedure.6 This is where OSSIX® Plus excels, offering a predictable and reliable resorption pattern that ensures excellent healing and clinical results1-6.
Key Advantages of OSSIX® Plus:
- Extended Barrier Functionality: OSSIX® Plus provides a resilient barrier for 4-6 months, allowing ample time for tissue regeneration and integration.1-2,4
- Degradation Resistance: Unlike many other membranes, OSSIX® Plus resists degradation even when exposed for 3-5 weeks,3 maintaining its protective function throughout the critical healing period.1-2,4
- Exceptional Handling Properties: With its adaptability and conformability, OSSIX® Plus adheres seamlessly to tissue defects, making it easier for clinicians to apply and manage.4
- Biocompatibility and Longevity: Made from porcine type I collagen, OSSIX® Plus offers excellent biocompatibility and is designed to last, providing durable and safe application in a variety of dental procedures. 4*
Versatile Applications for Comprehensive Care*
OSSIX® Plus is versatile and can be used in a wide range of clinical procedures, including:
- Ridge Augmentation for Implant Placement: Supports ridge augmentation before, during, or after implant insertion, ensuring a stable foundation.
- Alveolar Ridge Preservation: Acts as a barrier to preserve the alveolar ridge post-extraction, preparing the site for future implants.
- Sinus Elevation: Stabilizes graft material over the window in lateral window sinus elevation procedures, aiding in bone regeneration.
- Treatment of Bone and Soft Tissue Defects: Used in intra-bony defects, recession defects with a coronally positioned flap, and furcation defects, promoting periodontal health and stability.
- Vertical Bone Loss in Implants: Effective in cases of vertical bone loss around implants, provided proper debridement and implant disinfection is achieved.
*For detailed guidance on indications and contraindications, refer to the Instructions for Use (IFU) available in our IFU Library.
Sizing Options:
OSSIX® Plus is available in three convenient sizes to fit your clinical needs:
| 15×25 mm | 25×30 mm | 30×40 mm |
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*Images shown are not to scale.
list of references References1. Scheyer T. and. McGuire MK. (2014) Evaluation of Premature Membrane Exposure and Early Healing in Guided Bone Regeneration of Peri-Implant Dehiscence and Fenestration Defects with a Slowly Resorbing Porcine Collagen Ribose Cross-Linked Membrane: A Consecutive Case Series. Clinical Advances in Periodontics. 5: 165-170
2. Zubery Y, Nir E, and Goldlust A. (2008). Ossification of a Collagen Membrane Cross-Linked by Sugar: A Human Case Series. Journal of Periodontology, 79(6), 1101–1107
3. Hong HR, Chen C-Y, Kim DM, and Machtei EE. (2018). Ridge preservation procedures revisited: a randomized controlled trial to evaluate dimensional changes with two different surgical protocols. Journal of Periodontology.
4. Data on file.
5. Smukler, H., D. Capri, and L. Landi, Harvesting bone in the recipient sites for ridge augmentation. Int J Periodontics Restorative Dent, 2008. 28(4): p. 411-9.
6. Moses O, Vitrial D, Aboodi G, Sculean A, Tal H, Kozlovsky A, Artzi Z, Weinreb M, Nemcovsky. Biodegradation of Three Different Collagen Membranes in the Rat Calvarium: a Comparative Study. CE J Periodontol. 2008 May;79(5):905-11. doi: 10.1902/jop.2008.070361
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WarningReferences1. Scheyer T. and. McGuire MK. (2014) Evaluation of Premature Membrane Exposure and Early Healing in Guided Bone Regeneration of Peri-Implant Dehiscence and Fenestration Defects with a Slowly Resorbing Porcine Collagen Ribose Cross-Linked Membrane: A Consecutive Case Series. Clinical Advances in Periodontics. 5: 165-170
2. Zubery Y, Nir E, and Goldlust A. (2008). Ossification of a Collagen Membrane Cross-Linked by Sugar: A Human Case Series. Journal of Periodontology, 79(6), 1101–1107
3. Hong HR, Chen C-Y, Kim DM, and Machtei EE. (2018). Ridge preservation procedures revisited: a randomized controlled trial to evaluate dimensional changes with two different surgical protocols. Journal of Periodontology.
4. Data on file.
5. Smukler, H., D. Capri, and L. Landi, Harvesting bone in the recipient sites for ridge augmentation. Int J Periodontics Restorative Dent, 2008. 28(4): p. 411-9.
6. Moses O, Vitrial D, Aboodi G, Sculean A, Tal H, Kozlovsky A, Artzi Z, Weinreb M, Nemcovsky. Biodegradation of Three Different Collagen Membranes in the Rat Calvarium: a Comparative Study. CE J Periodontol. 2008 May;79(5):905-11. doi: 10.1902/jop.2008.070361
