Ossifying Collagen Barrier Membrane
Powered by GLYMATRIX® Technology1
for Guided Bone (GBR) and Tissue (GTR) Regeneration
Why Choose OSSIX® Plus?
- Extended Barrier Functionality: Provides up to 6 months of barrier function, ensuring optimal protection during the critical healing period2,3-6
- Degradation Resistance: Has long-lasting resistance to degradation. When exposed, it remains resistant for 3-5 weeks7
- Exceptional Handling: conforms easily to the shape of the alveolar ridge8-9
- Resorbable and Biocompatible: Integrates with surrounding tissues3-7, eliminating the need for site re-entry for removal3-7
- Proven Efficacy: Powered by GLYMATRIX® Technology,1 backed by clinical studies and real-world applications1-9
Applications of OSSIX® Plus
OSSIX® Plus is versatile and can be used in a wide range of clinical procedures, including:
- Alveolar ridge preservation consequent to tooth (teeth) extraction(s)
- Over the window in lateral window sinus elevation procedures
- Ridge augmentation around implants inserted
- In implants with vertical bone loss due to infection, only in cases where satisfactory debridement and implant surface disinfection can be achieved
- For treatment of recession defects, together with coronally positioned flap
- Simultaneous ridge augmentation and implant insertions
*For detailed guidance on indications and contraindications, refer to the Instructions for Use (IFU) available in our IFU Library.
Sizing Options:
OSSIX® Plus is available in three convenient sizes to fit your clinical needs:
| 15×25 mm | 25×30 mm | 30×40 mm |
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*Images shown are not to scale.
References1. Data on file (GLYMATRIX® based products legacy doc)
2. Zubery Y Goldlust, A. Alves, A Nir E (2007) Ossification of a novel cross-linked porcine collagen barrier in guided bone regeneration in dogs. JPeriodontol 78:112-121.
3. Zubery Y, Nir E, and Goldlust A. (2008). Ossification of a Collagen Membrane Cross-Linked by Sugar: A Human Case Series. Journal of Periodontology, 79(6), 1101–1107
4. Levin, B.P. and Y. Zubery, Use of a Sugar Cross-Linked Collagen Membrane Offers Cell Exclusion and Ossification. Compend Contin Educ Dent (15488578), 2018. 39(1): p. 44-48
5. Tal H, Kozlovsky A, Artzi Z, Nemcovsky CE, Moses O. Long-term Bio-degradation of Cross-Linked and Non-Cross-Linked Collagen Barriers in Human Guided Bone Regeneration. Clin Oral Implants Res. 2008 Mar;19(3):295-302. doi: 10.1111/j.1600-0501. 2007. 01424.x. Epub 2008 Jan 7.
6. Klinger A, Asad R, Shapira L, Zubery Y. (2010) In vivo Degradation of Collagen Barrier Membranes Exposed to the Oral Cavity. Clin. Oral Impl. Res. 21, 873–876
7. Hong HR, Chen C-Y, Kim DM, and Machtei EE. (2018). Ridge preservation procedures revisited: a randomized controlled trial to evaluate dimensional changes with two different surgical protocols. Journal of Periodontology
8. Data on file (Wet Adherence Property of OSSIX® Plus and OSSIX® Volumax Design Requirement)
9. Data on file (User Feedback Survey report 2024. Out of 33 respondents, 55% stated that it is very easy to use, while 36% said it is easy to use)
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