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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Randomized controlled trial on lateral augmentation using two collagen membranes: morphometric results on mineralized tissue compound

Friedmann A, Gissel K, Soudan M, Kleber BM, Pitaru S, Dietrich T.  J Clin Periodontol. 2011;38: 677-685. doi:10.1111/j.1600-051X.2011.01738.x

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