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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.text text
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PR590: Preliminary data upon μCT analysis indicate benefits in placing ribose crosslinked collagen materials across extraction socket compared to native collagen membranes in beagles

Friedmann A, Fischer K, Dalloul M, Yildiz MS, Kauffmann F, Fickl S. J Clin Periodontol. 2018;45(S19):321. doi:10.1111/jcpe.592_12915.

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