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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Ossification and Bone Regeneration in a Canine GBR Model, Part 1: Thick vs Thin Glycated Cross-Linked Collagen Devices

Paolo Pesce, Yuval Zubery, Arie Goldlust, Thomas Bayer, Roberto Abundo, Luigi Canullo

Int J Oral Maxillofac Implants. 2023 Jul-Aug;38(4):801-810.

Is this study glycated multilayered membranes (OSSIX® Volumax) were compared to a commercially available thin-layer membrane (OSSIX® Plus) in a lateral ridge augmentation model in dogs. Test groups presented significantly higher values compared to the empty control for all the endpoints. Conclusions: Within its limitations, this in-vivo study highlighted that those multilayered thick glycated membranes could serve as effective occlusive barriers for up to 6 months.

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