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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Long-term bio-degradation of cross-linked and non-cross-linked collagen barriers in human guided bone regeneration

Tal H, Kozlovsky A, Artzi Z, Nemcovsky CE, Moses O. Clin Oral Implants Res. 2008;19(3):295-302. doi: 1111/j.1600-0501.2007.01424.x

 

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