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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Das Verhalten einer Ribose-kreuzvernetzten Membran bei früher Exposition [German]

Zubery Y.  Implantologie J. 6. 2015.

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