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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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A clinical study on bone formation using a demineralized bone matrix and resorbable membrane

Kim YK, Kim SG, Lim SC, Lee HJ, Yun PY. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(6):e6-11. doi: 10.1016/j.tripleo.2010.01.012.

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