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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Ossification of a novel cross-linked porcine collagen barrier in guided bone regeneration in dogs

Zubery Y, Goldlust A, Alves A, Nir E. J Periodontol. 2007;78(1):112-121. doi:10.1902/jop.2007.060055.

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