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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Clinical evaluations of OSTEON as a new alloplastic material in sinus bone grafting and its effect on bone healing

Kim YK, Yun PY, Lim SC, Kim SG, Lee HJ, Ong JL. J Biomed Mater Res B Appl Biomater. 2008;Jul;86(1):270-277.

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