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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Three-dimensional bone regeneration of alveolar ridge defects using corticocancellous allogeneic block grafts: histologic and immunohistochemical analysis.

Jun CM, Yun JH.  Int J Periodontics Restorative Dent. 2016;36(1):74-81. doi:10.11607/prd.1950.

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