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OSSIX® Plus must not be used in patients with known collagen hypersensitivity, sensitivity to porcine-derived materials, or suffer from autoimmune diseases and connective tissue diseases. As the membrane is of a collagen origin, allergic reactions may not be entirely excluded. Please read IFU before use and for additional information on indications, contraindications, warnings and precautions.
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Histologic comparison of healing after ridge preservation using human demineralized bone matrix putty with one versus two different – sized bone particles

Hoang TN, Mealey BL. J Periodontol. 2012;83:174-181. doi: 10.1902/jop.2011.110209.

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